Transient severe thrombocytopenia with SARS-Cov-2 (COVID-19) infection in pregnancy

A 24-weeks pregnant woman in her 2nd pregnancy presented with mild COVID symptoms and new onset rapidly progressive severe thrombocytopenia a nadir of 20×109/L. She did not have any bleeding manifestations the platelet counts recovered over 3 days without need steroids or immunoglobulin treatment. COVID-19 infection may cause transient thrombocytopenia, this has been previously reported second trimester pregnancy. We speculate to be immune mediated. Other causes for were excluded after comprehensive investigations. This raise concerns on thromboprophylaxis anticoagulant use early pregnancies infected COVID-19. Assessing at least two occasions few apart an patient safer approach if continuing anticoagulants.